Goldenseal (Hydrastis Canadensis) is a perennial herb that has been used traditionally by Native American tribes as a medicine and natural dye as well as in modern pharmacology, for its anti-inflammatory and antibacterial properties. It is considered to be an herbal antibiotic and has been used to specifically treat infections of the mucous membranes. We use it in our Colds CX formulation because studies have shown it acts as a potent antioxidant, anti-inflammatory, and antibacterial compound.
Goldenseal contains a range of isoquinoline alkaloids, such as berberine, berberastine, hydrastine, and canadine. It is generally standardized to hydrastine and berberine for pharmacology, as these have shown to provide anti-inflammatory, antiseptic, and cardiovascular benefits. The alkaloid canadine has also been observed to soothe irritated mucous membranes in the throat and fight infections, but more studies need to be done to confirm these properties.
Antimicrobial Constituents from Goldenseal (the Rhizomes of Hydrastis canadensis) against Selected Oral PathogensIn Vivo Effects of Goldenseal, Kava Kava, Black Cohosh, and Valerian on Human Cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 Phenotypes